Doing those exact steps does not crash my machine. If these steps would crash every s2400 everytime, a lot more people would have made a bug report, because those a the basic steps you make whenever you make something new.
Can you be more specific on what it is exactly that you are doing? So what sample (length, sample rate, bit depth) do you load on which pad, at what moment? Do you leave the assign page and enter main screen? How do you record the pattern (live, tr, step)? Do you use multimode anywhere? Etc?